Product image is illustrative. Your medication and packaging may look different.
No. 11 · Women's Health
Progesterone
Oral micronized capsules
Oral micronized progesterone is an FDA-approved hormone, the generic of Prometrium, most often used with estrogen to protect the lining of the uterus during menopause hormone therapy. RULE Longevity offers progesterone capsules from $129 a month after a licensed provider reviews your history.
| Option | Monthly | Start |
|---|---|---|
| Progesterone capsules | $129per month | Start |
- Online visit and licensed provider review
- Medication and supplies, if prescribed
- Shipping in discreet packaging
- Messaging with your care team
- Cancel anytime before your next billing date
If you are not prescribed, no medication ships and no subscription starts. Questions first? Use our contact form.
Who it's for
- Women with a uterus who use estrogen for menopause symptoms
- Women in perimenopause or menopause whose provider recommends it
Not for
- A history of breast cancer, blood clots, stroke or heart attack
- Unexplained vaginal bleeding
- Liver disease
- Allergy to peanuts, since capsules may contain peanut oil
Your licensed provider reviews your full history and decides what is appropriate.
How it works
Complete the online women's health visit
A licensed provider reviews your history and screenings
If prescribed, capsules ship from a licensed US pharmacy
Your provider reviews your plan at follow-ups
What's included
- Online visit and licensed provider review
- Generic micronized progesterone capsules
- Discreet shipping
- Follow-up messaging
Important safety information
- Drowsiness and dizziness are common, so it is usually taken at bedtime. Do not drive if it makes you sleepy.
- Other effects can include breast tenderness, headache, mood changes and spotting.
- Report chest pain, sudden leg swelling, sudden vision changes, stroke symptoms or unusual bleeding right away.
Prescription only. A licensed provider reviews your health history in an online visit and decides whether this program is appropriate for you. Tell your provider about every medication, supplement, allergy and condition, and whether you are pregnant, trying to conceive or breastfeeding. If you have a severe reaction, trouble breathing, chest pain or swelling of the face or throat, call 911.
Full details: safety information. Updated October 28, 2026.
Do I need progesterone if I use estrogen?
If you have a uterus and use estrogen, a provider usually prescribes progesterone too, because it protects the lining of the uterus. If you do not have a uterus, you may not need it. Your provider decides based on your health history.
Is oral micronized progesterone the same as Prometrium?
Yes. Oral micronized progesterone capsules are the generic of Prometrium, an FDA-approved drug. RULE Longevity offers them at $129 per month with shipping included.
Can progesterone help with perimenopause symptoms?
Some providers prescribe progesterone during perimenopause or menopause based on your symptoms and health history. Results vary, and it is not right for everyone. Complete the online visit so a provider can review your situation.
What are the side effects of oral progesterone?
Common side effects include drowsiness, dizziness, breast tenderness and headache, so many people take it at bedtime as the label directs. Serious risks apply when it is used with estrogen. Your provider reviews your history and explains the risks.
Read more
Health GuideReady to start?
A licensed provider reviews your online visit and decides whether Progesterone is right for you.